【文獻解讀】ABCA12敲除或可配合靶向藥進行胰腺癌治療-廈門?；锟萍加邢薰?/title> <link rel="stylesheet" type="text/css" href="/skins/519068/css/style.css"/> <script type="text/javascript" src="/skins/519068/js/jquery.pack.js"></script> <script type="text/javascript" src="/skins/519068/js/jquery.SuperSlide.js"></script>  <script language="javascript" type="text/javascript"> var nav= '5'; </script>  <link rel="shortcut icon" href="/skins/519068/favicon.ico"> <script type="application/ld+json"> { "@context": "https://ziyuan.baidu.com/contexts/cambrian.jsonld", "@id": "http://www.51player.com/Article-3313949.html", "title": "【文獻解讀】ABCA12敲除或可配合靶向藥進行胰腺癌治療", "pubDate": "2023-04-03T11:26:06", "upDate": "2023-04-03T13:12:55" }</script> <script> (function(){ var bp = document.createElement('script'); var curProtocol = window.location.protocol.split(':')[0]; if (curProtocol === 'https') { bp.src = 'https://zz.bdstatic.com/linksubmit/push.js'; } else { bp.src = 'http://push.zhanzhang.baidu.com/push.js'; } var s = 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max-width: 100%; clear: both; min-height: 1em; text-align: center; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><img class="rich_pages wxw-img __bg_gif" data-galleryid="" data-ratio="0.18840579710144928" data-src="https://mmbiz.qpic.cn/mmbiz_gif/SJyibI36BxE2dpMUSxTyXdKLeiceFrGypQE9wrdsOt6uWeslCJyY2h8VZXH86n6icmLoGY1ZJE6sicjFNasFscoRtg/640?wx_fmt=gif" data-type="gif" data-w="690" data-index="1" src="https://img64.chem17.com/9/20230310/638140522385672773918.jpg" _width="677px" data-order="0" alt="圖片" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; vertical-align: bottom; height: auto !important; visibility: visible !important; width: 677px !important;"/></p><p><br/></p><section data-role="outer" label="edit by 135editor" style="margin: 0px 0px 24px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section data-tools="135編輯器" data-id="121531" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: space-between; align-items: flex-end; font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 6px; height: 6px; border-width: 1px; border-style: solid; border-color: rgb(0, 112, 192); overflow: hidden; visibility: visible;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></section></section></section><section style="margin: -1px 5px; padding: 15px 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; border-width: 1px; border-style: solid; border-color: rgb(0, 112, 192); visibility: visible;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; letter-spacing: 1.5px; background-image: initial; background-position: initial; background-size: initial; background-repeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial; visibility: visible;"><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; background-color: rgb(255, 255, 255); font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif; visibility: visible; overflow-wrap: break-word !important;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; color: rgb(68, 91, 106); background: transparent; visibility: visible;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; font-family: Helvetica, Arial, sans-serif; visibility: visible;">胰腺癌，即胰腺導管癌是一種消化系統的惡性腫瘤。在惡性腫瘤中它的發病率并不高，但其致死率卻是所有惡性腫瘤中最高的。它的癥狀隱匿，病因不明，早期確診率不高，常被誤診為腸胃病。通常發現時已經是晚期，同時可能帶有膽道梗阻、癥狀性糖尿病等并發癥。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 32px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; text-indent: 32px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; font-family: Helvetica, Arial, sans-serif; visibility: visible;">ABCA12是一種跨膜轉運蛋白，主要功能是運輸脂質，包括神經酰胺等。ABCA12的基因突變目前已被證實與三種常染色體隱性先天魚鱗病相關，因角質層細胞板層顆粒的脂質轉運異常，而引起脂質屏障畸形，有文獻表明，ABCA12作為脂質轉運體調節B細胞對胰島素的分泌。目前，ABCA12在某些腫瘤中存在高度表達的現象，但目前對其與腫瘤發展機制的研究卻鮮有報道。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 32px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 0em; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; letter-spacing: 0.544px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif; visibility: visible;"><img class="rich_pages wxw-img" data-backh="205" data-backw="526" data-ratio="0.3896551724137931" data-src="https://mmbiz.qpic.cn/mmbiz_png/SJyibI36BxE1JruT2X0icicicHsYx9QWAdbC0mIxODWW8bgIjjxApdJjwDEh6JN1ZOzJkN12CEQuYuDeI9BpaZAUVQ/640?wx_fmt=png" data-type="png" data-w="580" data-index="2" src="https://img64.chem17.com/9/20230310/638140522388016608854.png" _width="100%" crossorigin="anonymous" alt="圖片" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; vertical-align: inherit; height: auto !important; visibility: visible !important; width: 625px;"/></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 32px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 32px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; font-family: Helvetica, Arial, sans-serif; visibility: visible;">中國醫科大學盛京附屬醫院的團隊在通過對生物學信息庫獲取的基因表達矩陣處理，基因ID轉換等操作后發現胰腺癌樣本中ABCA12的表達量明顯高于正常胰腺樣本中的表達，而高表達的患者5年生存率明顯低于低表達的患者。</span></p></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255);"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; color: rgb(68, 91, 106); background: transparent;"><section style="margin: 10px 0px 20px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; justify-content: flex-start; display: flex; flex-flow: row nowrap; visibility: visible; overflow-wrap: break-word !important;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><img class="rich_pages wxw-img" data-backh="337" data-backw="526" data-ratio="0.6406533575317604" data-src="https://mmbiz.qpic.cn/mmbiz_png/SJyibI36BxE1JruT2X0icicicHsYx9QWAdbCHla2iaiaTaE87ibnNRyXia5WE3tNYxqZoh33XB3UHvamqvfW70xZibGgJfA/640?wx_fmt=png" data-type="png" data-w="551" data-index="3" src="https://img64.chem17.com/9/20230310/638140522391071621161.png" _width="100%" crossorigin="anonymous" alt="圖片" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; vertical-align: inherit; height: auto !important; width: 625px; visibility: visible !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif;">該團隊對ABCA12敲除后的SW1990細胞（人胰腺癌細胞）與未敲除的SW1990細胞進行了細胞遷移和細胞侵襲實驗。結果表明，敲除ABCA12后</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">SW1990</span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red font-family: Helvetica, Arial, sans-serif;">細胞的遷移能力、侵襲能力均大幅下降，其中，該團隊在侵襲實驗中使用了?；锷a<span style="font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; font-size: 15px; letter-spacing: 1.5px; text-align: justify; text-indent: 32px; background-color: rgb(255, 255, 255);">貨號：082706</span>的基質膠。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><img class="rich_pages wxw-img" data-backh="368" data-backw="526" data-ratio="0.6985559566787004" data-src="https://mmbiz.qpic.cn/mmbiz_png/SJyibI36BxE1JruT2X0icicicHsYx9QWAdbClmQQ5QkcaIuq1ufqZsHHcc9icUy864RPaiaEr2W7AOSnqzbq009HdafA/640?wx_fmt=png" data-type="png" data-w="554" data-index="4" src="https://img64.chem17.com/9/20230310/638140522393103085203.png" _width="100%" crossorigin="anonymous" alt="圖片" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; vertical-align: inherit; height: auto !important; width: 625px; visibility: visible !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; text-align: justify; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">同時流式細胞術結果顯示敲除ABCA12后，G0/G1期細胞數量減少，S期細胞數量顯著增加，表明ABCA12的下調主要通過抑制S期導致胰腺癌細胞的增殖停滯。細胞凋亡檢測結果顯示，細胞早期凋亡和晚期凋亡的總比例顯著增加，說明ABCA12抑制了細胞凋亡，而在加入治療藥物吉西他濱后各組癌細胞凋亡率均有提升，治療組的細胞凋亡率高于靶基因組敲除組，而共同處理組的細胞凋亡率是最高的。這表明下調ABCA12有助于治療藥物共同促進腫瘤細胞凋亡，因此，ABCA12可以促進胰腺癌細胞的增殖、轉移和抗凋亡。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><img class="rich_pages wxw-img" data-ratio="0.4774436090225564" data-src="https://mmbiz.qpic.cn/mmbiz_png/SJyibI36BxE1JruT2X0icicicHsYx9QWAdbCAZl5jeU2ibLLWwN3V3wRraQFCQz5ic0F6E58FegA8ZnxQEhyicTGUVhfg/640?wx_fmt=png" data-type="png" data-w="532" data-index="5" src="https://img64.chem17.com/9/20230310/638140522395301996360.png" _width="532px" crossorigin="anonymous" alt="圖片" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; vertical-align: inherit; height: auto !important; width: 532px !important; visibility: visible !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">免疫蛋白印跡試驗結果顯示，兩組細胞中AKT和PI3K蛋白的表達無明顯變化，磷酸化的P-AKT在ABCA12敲除細胞中的表達明顯低于陰性對照細胞。因此，ABCA12通過AKT通路誘導胰腺癌的發生發展。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-align: justify; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">Antiapoptotic Role of PPARβ in Keratinocytes via Transcriptional Control of the Akt1 Signaling Pathway一文中提到PPAR-δ通過轉錄調控激活AKT1的新通路，對角質形成細胞具有抗凋亡作用，據此作者認為AKT的抗凋亡作用可能是由于PPAR-δ的調控，并且PPAR-δ與ABCA12之間存在相互作用的機制。然而，目前尚不清楚PPAR-δ如何在角質形成細胞中與ABCA12相互作用，以及PPAR-δ的上調是否是對細胞凋亡的反應。在作者的研究中，胰腺腫瘤細胞和角質形成細胞可能存在不同的分化差異，在AKT通路的內部調控機制中可能存在更多的基因協同調控，有待進一步進一步研究。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><img class="rich_pages wxw-img" data-ratio="0.4244604316546763" data-src="https://mmbiz.qpic.cn/mmbiz_png/SJyibI36BxE1JruT2X0icicicHsYx9QWAdbCmcPAZQzkMDibyQYygWelaP1gI1Ku3gTNqCf79s29j01QhujTYO0XG7g/640?wx_fmt=png" data-type="png" data-w="556" data-index="6" src="https://img64.chem17.com/9/20230310/638140522396552168181.png" _width="556px" crossorigin="anonymous" alt="圖片" data-fail="0" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; vertical-align: inherit; height: auto !important; width: 556px !important; visibility: visible !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; text-indent: 0em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">本研究中使用?；锘|膠對ABCA12敲除后的SW1990細胞進行了transwell實驗。</span></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 32px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; flex-shrink: 0; visibility: visible; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; overflow-wrap: break-word !important;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; background-color: rgb(0, 112, 192); overflow: hidden; visibility: visible;"><section data-tools="135編輯器" data-id="121531" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 15px 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; border-width: 1px; border-style: solid; border-color: rgb(0, 112, 192); visibility: visible;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; line-height: 1.75em; visibility: visible;"><section data-tools="135編輯器" data-id="119886" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 20px 0px 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start; visibility: visible;"><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192); visibility: visible;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 14px; visibility: visible; font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;">和，類器官培養基自己配好還是購買商品化培養好</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center; visibility: visible;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); visibility: visible; transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255); visibility: visible;"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent; visibility: visible;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; visibility: visible; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; color: rgb(0, 0, 0); line-height: 1.6em; visibility: visible; font-family: Helvetica, Arial, sans-serif;">作為生命科學研究常用且最重要的方法，細胞體外培養技術直接影響了研究結果的準確性。傳統二維細胞培養模型，藥物無差別作用于每個細胞。細胞間作用力弱，類型單一，細胞貼壁生長，無法模擬體內的生長環境和空間結構。類器官培養不僅高度模擬體內細胞生長環境，保持細胞生長結構，擁有器官的部分功能特性，能更好地代表組織器官的生理功能和生物學特性。但現階段許多類器官原代建立尚存在成功率低，培養條件不穩定的情況。而使用合適、優秀的類器官培養基不僅是類器官培養成功的一大關鍵，還能省時省力節約科研成本。今天我們來聊聊類器官的培養基。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outlin: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section></section></section></section><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 14px; font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">用什么替代動物模型</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255);"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 0em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">參考資料</strong></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[1]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; caret-color:red font-family: Helvetica, Arial, sans-serif;">https://modernizetesting.org/congress-eliminates-1930s-animal-testing-requirement</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[2]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">https://www.science。。ｏｒｇ/content/article/fda-no-longer-needs-require-animal-tests-human-drug-trials#.Y76rZYPSO3g.twitter</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 0em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[3]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; text-align: justify; caret-color:red font-family: Helvetica, Arial, sans-serif;">https://science.sciencemag.org/content/371/6531/839</span></p></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">[4]</span></strong></span><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 15px; line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">https://medicalxpress.com/news/2022-02-infusion-3d-cellular-intestine.html</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><section data-tools="135編輯器" data-id="122329" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section style="margin: 10px auto; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><section data-width="100%" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 0px; height: 0px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section><section style="margin: 0px; padding: 10px 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: center; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 15px;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(218, 42, 47); text-align: center;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-size: 12px; color: rgb(127, 127, 127); font-family: Helvetica, Arial, sans-serif;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">?；惼鞴倥囵B案例</strong></span></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 15px;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; line-height: 1.75em; color: rgb(71, 71, 71);"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; justify-content: flex-start;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; flex-shrink: 0;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 24px; overflow: hidden;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 16px; color: rgb(0, 112, 192);"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">關于?；?/strong></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: flex; align-items: center;"><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; width: 7px; height: 14px; border-left: 1px solid rgb(0, 112, 192); border-right: 1px solid rgb(0, 112, 192); transform: skew(-30deg);"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></section></section></section><section style="margin: 10px 0px 0px; padding: 10px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; background-color: rgb(255, 255, 255);"><section data-autoskip="1" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.75em; background: transparent;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.6em; color: rgb(38, 38, 38); font-size: 15px; font-family: Helvetica, Arial, sans-serif;">廈門?；锟萍加邢薰荆╔iamen Mogengel）位于中國·廈門國家高新技術創業中心；公司致力于3D細胞培養核心原材料的研發與產業化升級，是國內一家從科研做起，從實驗研究中一路走來的全流程自主研發、自主生產的企業。目前公司的產品有基質膠、類器官培養基、細胞因子、3D細胞培養耗材、3D細胞培養智能顯微鏡等；公司擁有4大技術研發中心：分子克隆和細胞編輯中心、實驗動物中心、蛋白表達和純化平臺、類器官質檢系統和自動化。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 28px; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; line-height: 1.6em; color: rgb(38, 38, 38); font-size: 15px; font-family: Helvetica, Arial, sans-serif;"> 團隊擁有十余年類器官技術研究基礎，實力雄厚，科研意志堅定，學術態度嚴謹，大膽嘗試，勇于創新。公司推出的基質膠、類器官培養試劑盒等產品廣泛適用于類器官培養、血管生成實驗、細胞侵襲（transwell）實驗、PDX、CDX模型實驗、腫瘤球培養、腫瘤移植、皮下成瘤實驗、干細胞培養及細胞分化研究等。</span></p></section></section></section></section></section></section></section></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; color: rgb(0, 112, 192);"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; font-family: Helvetica, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;">?；|膠</strong></span></section><section style="margin: 0px; padding: 0px 5px; outline: 0px; max-width: 100%; box-sizing: border-box; display: flex; align-items: center; font-family: system-ui, 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!important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">?；|膠具有低內毒素、兼容性高、批間穩定性高等優點，嚴格完善的質檢體系為各位學者老師的實驗研究保駕護航；清澈透亮的膠滴為類器官的顯微觀測與數據分析減少障礙。既有價格實惠性能優異的高性價比產品，又有暢所欲言互幫互助的各實驗交流地，因此?；|膠飽受國內外用戶青睞。同時?；锲诖c各位學者老師在類器官的交流，若您將研究發文與?；锓窒?，將得到?；锏莫剬W金。</span></p><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; text-indent: 0em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">【發文有獎】引用MG&ABW基質膠，瓜分百萬獎學金！</span></section><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; text-indent: 27px; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; font-family: system-ui, -apple-system, BlinkMacSystemFont, Arial, sans-serif; box-sizing: border-box !important; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; color: rgb(0, 0, 0); font-size: 15px; background-color: transparent; caret-color:red line-height: 1.6em; font-family: Helvetica, Arial, sans-serif;">?；锲诖c各位學者老師的合作交流。</span></p></section></section></section></section></section></section></section></section></section><section data-role="paragraph" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; font-family: mp-quote, -apple-system-font, BlinkMacSystemFont, Arial, sans-serif;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; clear: both; min-height: 1em; box-sizing: border-box !important; overflow-wrap: break-word !important;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; color: rgb(34, 34, 34); font-size: 17px; letter-spacing: 0.544px; text-align: justify; white-space: normal; background-color: rgb(255, 255, 255); box-sizing: border-box !important; overflow-wrap: break-word !important;"/></p></section></section></section><p><br/></p><p><br/></p><p><br/></p><p><br/></p><p><br/></p><p><br/></p> </div> <div 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